Oxford Handbook of Sleep Medicine by Guy Leschziner
Author:Guy Leschziner
Language: eng
Format: epub, pdf
Publisher: OUP Oxford
Published: 2021-05-15T00:00:00+00:00
Chapter 18
REM sleep behaviour disorder
Laura Pérez-Carbonell and Guy Leschziner
Introduction
Clinical features
Diagnostic criteria
The significance of RBD
Pathophysiology
Differential diagnosis
Management
Conclusion
Introduction
Rapid eye movement sleep behaviour disorder (RBD) is a parasomnia characterized by abnormal behaviours arising during REM sleep. Described for the first time in humans just over 30 years ago, RBD is a condition of increasing clinical and research interest.
Two forms of RBD have been identified: idiopathic (primary) and symptomatic (secondary). Idiopathic RBD may be the initial form of presentation of a neurodegenerative disorder. The secondary form of RBD is associated with established neurological disorders, such as Parkinsonâs disease (PD), dementia with Lewy bodies (DLB), multisystem atrophy (MSA), or narcolepsy.
The exact prevalence of idiopathic RBD is unknown, but it has been estimated that it affects <2% of the population aged >60 years. There is a male predominance in the condition, although female cases may be under-recognized.
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