Oxford Handbook of Sleep Medicine by Guy Leschziner

Oxford Handbook of Sleep Medicine by Guy Leschziner

Author:Guy Leschziner
Language: eng
Format: epub, pdf
Publisher: OUP Oxford
Published: 2021-05-15T00:00:00+00:00


Chapter 18

REM sleep behaviour disorder

Laura Pérez-Carbonell and Guy Leschziner

Introduction

Clinical features

Diagnostic criteria

The significance of RBD

Pathophysiology

Differential diagnosis

Management

Conclusion

Introduction

Rapid eye movement sleep behaviour disorder (RBD) is a parasomnia characterized by abnormal behaviours arising during REM sleep. Described for the first time in humans just over 30 years ago, RBD is a condition of increasing clinical and research interest.

Two forms of RBD have been identified: idiopathic (primary) and symptomatic (secondary). Idiopathic RBD may be the initial form of presentation of a neurodegenerative disorder. The secondary form of RBD is associated with established neurological disorders, such as Parkinson’s disease (PD), dementia with Lewy bodies (DLB), multisystem atrophy (MSA), or narcolepsy.

The exact prevalence of idiopathic RBD is unknown, but it has been estimated that it affects <2% of the population aged >60 years. There is a male predominance in the condition, although female cases may be under-recognized.



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